Friday, 27 May 2016

GTV (gross tumor volume)

It is the volume that includes palpable, visible, or demonstrable extent of a tumor. It may consist of the primary tumor, metastatic disease, or lymphadenopathy. It usually represents the part of the malignant growth where the tumor cell density is the largest [1]. It is the best estimate of tumor volume visualized by radiological, computed tomography scan, magnetic resonance, ultrasound imaging, or positron emission tomography [2].
Bibliographic references:
[1] Fisher, B. and Daugherty, L. (2013). G. In: L. Brady and T. Yaeger, ed., Encyclopedia of Radiation Oncology, 1st ed. Springer-Verlag Berlin Heidelberg, pp.295-304.
[2] Fowler, J. (2006). Part I: Basic Concepts in Treatment Planning, 1. Practical Time-Dose Evaluations, or How to Stop Worrying and Learn to Love Linear Quadratics. In: S. Levitt, J. Purdy, C. Perez and S. Vijayakumar, ed., Technical Basis of Radiation Therapy, Practical Clinical Applications, 4th ed. Springer-Verlag Berlin Heidelberg, pp.3-31.