Tuesday, 10 May 2016

EQD2

Biologically equivalent total dose at 2 Gy/fraction, considering certain α/β [1,2]. The total dose of a schedule using 2 Gy per fraction that gives the same log cell kill as the schedule in question [2].
Bibliographic references:
[1] Hijazi H, Chevallier D, Gal J, Chand M, Gautier M, Hannoun-Levi J. Prostate cancer boost using high-dose-rate brachytherapy: early toxicity analysis of 3 different fractionation schemes. jcb. 2013;4:203-209. doi:10.5114/jcb.2013.38657.
[2] Fowler, J. (2006). Part I: Basic Concepts in Treatment Planning, 1. Practical Time-Dose Evaluations, or How to Stop Worrying and Learn to Love Linear Quadratics. In: S. Levitt, J. Purdy, C. Perez and S. Vijayakumar, ed., Technical Basis of Radiation Therapy, Practical Clinical Applications, 4th ed. Springer-Verlag Berlin Heidelberg, pp.3-31.