2020 ESMO awards

Deadline for nominations: 16 February 2020.

Nominate here: 2020 ESMO Award Nominations. ESMO. https://www.esmo.org/career-development/awards/esmo-award-nominations?utm_campaign=2020%20ESMO%20Awards&utm_source=hs_email&utm_medium=email&utm_content=82702576&_hsenc=p2ANqtz-917J9qQf3PoiJdQ31axYuQiW6rm8pkQgp8wDmxQ5CsS9r-duoYXvYjsSYx-6IijSkwgNUEjU3lvoGSgmOre7nynDFv9g&_hsmi=82702576. Published 2020. Accessed January 31, 2020.

Rs of radiobiology

The most important biological factors influencing tumor and normal tissue responses to fractionated treatment are referred to as the Rs [1]:

1. Repair [1]/Recovery [2];
2. Re-assortment/Redistribution [1,2];
3. Repopulation [1,2];
4. Reoxygenation [1,2];
5. Radiosensitivity [1,2];
6. Reactivation of anti-tumor immune response [1];
7. intrinsic Radiosensitivity [2];
8. iRradiated volume [2];
9. long-term Restoration [2];
10. molecular Radiopathology [2].

Bibliographic references:

[1] Boustani J, Grapin M, Laurent PA, Apetoh L, Mirjolet C. The 6th R of Radiobiology: Reactivation of Anti-Tumor Immune Response. Cancers (Basel). 2019 Jun 20;11(6):860. Available at: https://dx.doi.org/10.3390%2Fcancers11060860.

[2] Dörr W. Radiobiology of tissue reactions. Ann ICRP. 2015;44(1 Suppl):58–68. Available at: https://doi.org/10.1177/0146645314560686.

PD-1 checkpoint inhibitors

A PD-1 (programmed cell death protein 1) inhibitor fairy tale:

How do tumors use PD-1 to cause T-cell exhaustion? Learn how overexpression of PD-1 receptors on T cells may lead to T-cell exhaustion:

ESTRO-ASTRO definition of oligometastatic disease - public comment survey

The deadline to submit comments is Monday, January 6th, 2020: ESTRO-ASTRO definition of oligometastatic disease - public comment survey.