Tuesday 11 December 2018

Chemo-Radiotherapy of Oligometastases of Colorectal Cancer With Pegylated Liposomal Mitomycin-C Prodrug (Promitil): Mechanistic Basis and Preliminary Clinical Experience

Chemo-Radiotherapy of Oligometastases of Colorectal Cancer With Pegylated Liposomal Mitomycin-C Prodrug (Promitil): Mechanistic Basis and Preliminary Clinical Experience: Hypo-fractionated radiotherapy and stereotactic body radiotherapy are viable options for treatment of oligometastases. A prodrug of mitomycin-C is under clinical testing as a pegylated liposomal formulation (Promitil) with an improved safety profile over mitomycin-C. Promitil was offered to two patients with oligometastases from colorectal cancer as radiosensitizer. Each derived durable clinical benefit from Promitil administered immediately prior to and following irradiation. Transient toxicity to normal tissues of moderate to severe degree was observed. Promitil appears to have potential clinical value in this setting.

7 comments:

  1. Believe me I have used Dr Aziba herbal Medicine cure remedy for 2 WEEKS now. So far, it has cured my HERPES, eliminated my COLD SORE, improved energy and metabolism, in the morning I feel recharged and I no longer feel sleepy after a meal. As for the scent, it does smell like motor oil but I chase it down with 100% Herbal medicine from Dr Aziba. twice a day AFTER a meal. I also experienced vivid dreams for about 5 days now it’s diminishing to during the first 2 or 3 hours of sleep . contact Dr Aziba: EMAIL: priestazibasolutioncenter@gmail.com or whatsapp +2348100368288 and He also have herbs medicine to cure some popular diseases....
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  2. I'm so happy to testify of the good work of Dr Agbomina , I Suffer from Herpes virus since 2007 and i had frequent symptoms in my private area, after some time it will go away after using acyclovir drugs, then come back after some months. it was disheartening since i have been diagnosed, but after finding Dr Agbomina and his reviews i was convinced that he will definitely cure me and so i contacted and he told me how to get his medicine and using it for just 14 days and i will go and check up and first i said how can that be possible but i used his herbal medicine after making purchase and truly i used it and went for the test again, and my result came back negative. so i made it a task to share this good testimony in the internet so that those sick can benefit and get cured. What app or call: +2349039139161 Or Email: dragbonherbalmedicine@gmail.com

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  4. Hello everyone i’m so grateful to DR. KOFI for curing me completely from herpes virus . I was told i have herpes in 2011, i have been taking different kinds of medication still yet no improvement until i saw testimonies of DR. KOFI curing Herpes, Diabetes, HIV and other disease i was skeptical about contacting him but i also knew the importance of herbal medicine, i made up my mind and contacted him we talked on phone and he prepared and gave me medicine which i took according to his dosage information. Now I’m so happy I’m cured from Herpes my heart is so filled with joy, thank you so much DR. KOFI . If you are reading this and you have Herpes or any kind of disease contact him today Email: drkofiherbalcure@gmail.com .. for a solution

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  6. FINALLY FREE FROM HERPES VIRUSI thought my life had nothing to offer anymore because life became meaningless to me because I had herpes virus, the symptoms became very severe and bold and made my family run from and abandoned me so they won't get infected. I gave up everything, my hope, dreams,vision and job because the doctor told me there's no cure. I consumed so many drugs but they never cured me but hid the symptoms inside me making it worse. I was doing some research online someday when I came across testimonies of some people of how DR ADIGBA cured them from herpes, I never believed at first and thought it was a joke but later decided to contact him on the details provided and when I messaged him we talked and he sent me his herbal medicine and told me to go for a test after two weeks. Within 7 days of medication the symptoms disappeared and when I went for a test Lo and behold I was NEGATIVE by the Doctor Who tested me earlier. Thank you DR ADIGBA because I forever owe you my life and I'll keep on telling the world about you. If you are going through same situation worry no more and contact DR ADIGBA via dradigba@gmail. com or WhatsApp him via +2348077875210. he is good too to cure all type of disease and virus. 1 HIV cure 2 cancer 3 diabetes 4 hepatitis 5 herpes. You can contact if you are having any problem...

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